Recently, there has been a focus on using biopolymer-based particles to stabilize high internal phase Pickering emulsions (HIPPEs) due to the notable advances in biocompatibility and biodegradability. In this work, the complex particles of peanut protein isolate and carboxymethyl cellulose (CMC) with various substitution degrees (DS; 0.7 and 0.9) and weight average molecular weights (Mw; 90, 250, and 700 kDa) were prepared and characterized as novel stabilizers. For the obtained four types of morphologically distinct particles, the complex particles formed by CMC (0.9 DS and 250 kDa) showed cluster structures with an average size of 1.271 μm, equally biphasic wettability with three-phase contact angles of 91.5°, and the highest diffusion rate at the oil-water interface. HIPPEs stabilized by these particles exhibited more elastic behavior due to the smaller tanδ and higher viscosity, as well as excellent thixotropic recovery properties and stability against heating, storage, and freeze-thawing. Furthermore, confocal laser scanning microscopy verified that these particles formed a dense interfacial layer around the oil droplets, which could resist flocculation and coalescence between oil droplets during in vitro digestion. The improved bioaccessibility of curcumin-loaded HIPPEs made these delivery systems potentially apply in functional foods.

中文翻译：

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羧甲基纤维素对高内相皮克林乳液稳定性、流变性和姜黄素生物可及性的影响

最近，由于生物相容性和生物降解性方面的显着进步，使用生物聚合物基颗粒来稳定高内相皮克林乳液 (HIPPE) 成为人们关注的焦点。在这项工作中，制备了具有不同取代度（DS；0.7 和 0.9）和重均分子量（Mw；90、250 和 700 kDa）的花生分离蛋白和羧甲基纤维素（CMC）复合颗粒，并表征为新型颗粒。稳定剂。对于所获得的四种形态不同的颗粒，由CMC（0.9 DS和250 kDa）形成的复合颗粒显示出平均尺寸为1.271 μm的簇结构，具有相同的双相润湿性，三相接触角为91.5°，并且是最高的。油水界面的扩散速率。由这些颗粒稳定的 HIPPE 由于较小的 tanδ 和较高的粘度而表现出更好的弹性行为，以及优异的触变恢复性能和对加热、储存和冻融的稳定性。此外，共焦激光扫描显微镜证实这些颗粒在油滴周围形成致密的界面层，可以在体外消化过程中抵抗油滴之间的絮凝和聚结。负载姜黄素的 HIPPE 的生物可及性得到改善，使得这些输送系统有可能应用于功能性食品。