Plant pathogens are challenged by host‐derived iron starvation or excess during infection, but the mechanism of plant pathogens rapidly adapting to the dynamic host iron environments to assimilate iron for invasion and colonization remains largely unexplored. Here, we found that the GATA transcription factor SreC in Curvularia lunata is required for virulence and adaption to the host iron excess environment. SreC directly binds to the ATGWGATAW element in an iron‐dependent manner to regulate the switch between different iron assimilation pathways, conferring adaption to host iron environments in different trophic stages of C. lunata. SreC also regulates the transition of trophic stages and developmental processes in C. lunata. SreC‐dependent adaption to host iron environments is essential to the infectious growth and survival of C. lunata. We also demonstrate that CgSreA (a SreC orthologue) plays a similar role in Colletotrichum graminicola. We conclude that Sre mediates adaption to the host iron environment during infection, and the function is conserved in hemibiotrophic fungi.

中文翻译：

---

SreC依赖性对宿主铁环境的适应调节新月弯孢菌营养阶段的转变和发育过程

植物病原体在感染过程中受到宿主源性铁饥饿或过量的挑战，但植物病原体快速适应动态宿主铁环境以同化铁进行入侵和定殖的机制在很大程度上仍未被探索。在这里，我们发现 GATA 转录因子 SreC新月弯孢菌是毒力和适应宿主铁过量环境所必需的。SreC 以铁依赖性方式直接与 ATGWGATAW 元件结合，调节不同铁同化途径之间的转换，从而适应宿主不同营养阶段的铁环境。月形藻。SreC 还调节营养阶段和发育过程的转变月形藻。SreC 依赖性对宿主铁环境的适应对于感染性生长和生存至关重要月形藻。我们还证明 CgSreA（SreC 直系同源物）在禾谷炭疽病。我们得出结论，Sre 在感染过程中介导对宿主铁环境的适应，并且该功能在半生物营养真菌中是保守的。