Food allergy is postulated to originate from cutaneous sensitization through a disrupted skin barrier, particularly in atopic dermatitis (AD). Strategies for food allergy prevention currently centre around early allergic food introduction, but there is now increasing evidence for the role of early skin barrier restoration in the form of prophylactic emollient therapy and early aggressive, proactive treatment of established AD for food allergy prevention. Research gaps that remain to be addressed include the type of emollient or anti‐inflammatory medication, which confers the greatest efficacy in preventive or proactive skin treatment, respectively, the duration of therapy, and the window of opportunity for these interventions.

中文翻译：

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皮肤管理在预防特应性皮炎和食物过敏中的作用

食物过敏被认为是由皮肤屏障破坏引起的皮肤过敏引起的，特别是特应性皮炎 (AD)。目前，预防食物过敏的策略主要围绕早期引入过敏食物，但现在有越来越多的证据表明，以预防性润肤疗法和早期积极主动治疗已形成的 AD 的形式，早期皮肤屏障修复对于预防食物过敏具有重要作用。仍有待解决的研究空白包括润肤剂或抗炎药物的类型（分别在预防性或主动性皮肤治疗中具有最大功效）、治疗持续时间以及这些干预措施的机会窗口。