The enzyme market is growing constantly, and lipases, in their free and immobilized forms, constitute an important part of this market. This study aimed to analyze and discuss current market scenarios using data from the literature, focusing on lipases and the feasibility of their use in the immobilized form. It also compares the cost of biodiesel production using two commercial lipases: Eversa Transform 2.0 (free lipase) and Novozyme 435 (immobilized lipase). The results show that the European and North American enzyme markets are the most prominent worldwide, with Denmark and the USA as the major exporters and importers, respectively. Lipases can be used in a wide variety of fields, and immobilization brings many advantages to this enzyme class. Finally, we show the use of immobilized enzymes and lipases in biorefinery and food industries and carry out a comparative cost analysis to produce biodiesel using a free and immobilized lipase. We concluded that the enzyme market, in which lipases play an important role, is extensive, and that immobilized lipases seem to be excellent biocatalysts with feasible costs for industrial applications.

中文翻译：

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脂肪酶：固定化衍生物的市场研究和潜在应用

酶市场不断增长，游离和固定形式的脂肪酶构成了该市场的重要组成部分。本研究旨在利用文献数据分析和讨论当前的市场情况，重点关注脂肪酶及其以固定化形式使用的可行性。它还比较了使用两种商业脂肪酶生产生物柴油的成本：Eversa Transform 2.0（游离脂肪酶）和 Novozyme 435（固定化脂肪酶）。结果显示，欧洲和北美酶市场在全球范围内最为突出，其中丹麦和美国分别是主要出口国和进口国。脂肪酶可用于多种领域，固定化为此类酶带来了许多优势。最后，我们展示了固定化酶和脂肪酶在生物精炼和食品工业中的使用，并进行了使用游离和固定化脂肪酶生产生物柴油的成本比较分析。我们的结论是，脂肪酶在其中发挥重要作用的酶市场是广泛的，并且固定化脂肪酶似乎是优秀的生物催化剂，具有可行的工业应用成本。