Comprehensive SummaryA new, selective Ru(II)‐catalyzed alkynylation reaction of isoquinolones, quinazolones and phthalazinones with readily available bromoalkynes has been developed. This reaction enables the selective construction of a new C(sp2)‐C(sp) bond through C—H activation and C—Br functionalization, and offers an effective and selective route to synthesizing highly valuable alkynylated isoquinolone, quinazolone and phthalazinone derivatives with a wide substrate scope and high selectivity.

中文翻译：

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Ru(II)-催化异喹诺酮、喹唑酮和酞嗪酮与溴炔的选择性 C-H 炔基化反应

综合总结一种新的、选择性钌(II)催化的异喹诺酮、喹唑啉酮和二氮杂萘酮与容易获得的溴代炔烃的炔基化反应已经被开发出来。该反应能够选择性地构建新的 C(sp2通过CH活化和C-Br官能化形成)-C(sp)键，为合成具有广泛底物范围和高选择性的高价值炔基化异喹诺酮、喹唑酮和二氮杂萘酮衍生物提供了有效且选择性的路线。