Βiologic agents and small molecules have expanded the therapeutic armamentarium of moderate to severe ulcerative colitis (UC). However, their comparative efficacy and safety performance as maintenance treatments have not been sufficiently explored. We performed a systematic review and network meta-analysis (NWM) to assess the comparative efficacy and safety of all approved and emerging treatments for maintenance in moderate to severe UC.

中文翻译：

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所有生物制剂和小分子在溃疡性结肠炎中的维持性能比较：网络荟萃分析。

生物制剂和小分子扩大了中度至重度溃疡性结肠炎（UC）的治疗手段。然而，它们作为维持治疗的比较功效和安全性能尚未得到充分探索。我们进行了系统评价和网络荟萃分析 (NWM)，以评估所有已批准的和新兴的中度至重度 UC 维持治疗的比较疗效和安全性。