In recent years, the conventional preparation of silver nanoclusters (AgNCs) has attracted much attention due to their ultra-small size, tunable fluorescence, easy-to-engineer, as well as biocompatible material. Moreover, its great affinity towards cytosine bases on single-stranded DNA has led to the construction of biosensors, especially aptamers, for a broad variety of applications in food safety and environmental protection. In past years, numerous researchers paid attention to the construction of AgNCs aptasensor. Therefore, this review will be an effort to summarize the synthetic strategy along with the influences of factors on synthesis, categorize the sensing mechanism of aptamer-functionalized AgNCs biosensors, as well as their specific applications in food safety detection including heavy metal, toxin, and foodborne pathogenic bacteria. Furthermore, a brief conclusion and outlook regarding the prospects and challenges of their applications in food safety were drawn in line with the developments in DNA-AgNCs.

中文翻译：

---

荧光DNA-银纳米团簇在食品安全检测中的应用：从合成到应用

近年来，银纳米团簇（AgNCs）的常规制备因其超小尺寸、荧光可调、易于工程设计以及生物相容性材料而备受关注。此外，它对单链 DNA 上的胞嘧啶碱基具有很强的亲和力，因此可以构建生物传感器，特别是适体，在食品安全和环境保护方面具有广泛的应用。近年来，AgNCs适配体传感器的构建受到众多研究者的关注。因此，本综述将总结合成策略以及影响合成的因素，对适配体功能化AgNCs生物传感器的传感机制进行分类，以及它们在食品安全检测（包括重金属、毒素和有机物）中的具体应用。食源性致病菌。此外，根据DNA-AgNCs的发展，对其在食品安全中的应用前景和挑战进行了简要的总结和展望。