Background

Multi-factorial reasons are an induction to cause cancer. Different infections and infestations with viruses, bacteria, and parasites have been detected for many years to be related to human carcinogenesis.

Purpose

The study aimed to review all ideas of tumor carcinogenesis and its associations with parasitic infections and infestations.

Methods

We reviewed several articles (published and imprinted) by selecting, extracting, and synthesizing data about the relationship between cancers and parasites.

Results

Several helminths infections as schistosomiasis, are highly carcinogenic agents for bladder cancer, whereas trypanosomiasis has a bi-model role in cancer development. Leishmaniasis may be a cause of hepatocarcinoma, skin cancer, and lymphomas. In addition, malaria appears to be causative in the carcinogenesis of some cancers; as Burkitt lymphoma. Also, data from previous studies suggested that Strongyloides stercoralis may be a relevant co-factor in lymphomas.

Conclusion

There are different mechanisms of parasitic infection to be enhancing in carcinogenesis of cancer in human.

中文翻译：

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寄生与肿瘤致癌：综述主题

背景

多种因素共同诱发癌症的发生。多年来，人们已发现病毒、细菌和寄生虫的不同感染和侵扰与人类致癌有关。

目的

该研究旨在回顾肿瘤致癌及其与寄生虫感染和侵扰的关联的所有观点。

方法

我们通过选择、提取和综合有关癌症和寄生虫之间关系的数据，回顾了几篇文章（已发表和出版）。

结果

血吸虫病等几种蠕虫感染是膀胱癌的高度致癌剂，而锥虫病在癌症发展中具有双重作用。利什曼病可能是肝癌、皮肤癌和淋巴瘤的原因。此外，疟疾似乎是某些癌症的致癌因素。如伯基特淋巴瘤。此外，先前研究的数据表明，粪类圆线虫可能是淋巴瘤的相关辅助因子。

结论

寄生虫感染有不同的机制促进人类癌症的发生。