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Evaluating the mode of action of perfluorooctanoic acid-induced liver tumors in male Sprague-Dawley rats using a toxicogenomic approach
Journal of Environmental Science and Health, Part C ( IF 1.650 ) Pub Date : 2024-03-18 , DOI: 10.1080/26896583.2024.2327969
Xilin Li 1 , Zemin Wang 1 , Qiangen Wu 1 , James E. Klaunig 1
Affiliation  

The mode of action (MOA) underlying perfluorooctanoic acid (PFOA)-induced liver tumors in rats is proposed to involve peroxisome proliferator-activated receptor α (PPARα) agonism. Despite clear PPA...

中文翻译:

使用毒物基因组学方法评估全氟辛酸诱导的雄性斯普拉格-道利大鼠肝脏肿瘤的作用方式

全氟辛酸 (PFOA) 诱导大鼠肝脏肿瘤的作用模式 (MOA) 被认为涉及过氧化物酶体增殖物激活受体 α (PPARα) 激动。尽管有明确的 PPA...
更新日期:2024-03-18
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