ObjectivesTo promote posttraumatic growth (PTG) in colorectal cancer (CRC) couples, a couple‐based PTG intervention was conducted, and the intervention had previously proved be feasible in CRC couples. The current study was conducted to validate the effects of intervention in CRC couples.MethodThis is a randomized controlled study that included 174 CRC couples. All participants were randomized to either the intervention (usual care plus 5‐week PTG intervention, n = 87) or the control group (usual care, n = 87). Data were collected from CRC couple dyads at baseline and immediately post‐intervention periods. Primary outcome refers to positive changes, and secondary outcomes include marital satisfaction, quality of life (QOL), and anxiety and depression. Multilevel modeling was applied to analyze the intervention effects.ResultsParticipants in the program showed increased PTG, marital satisfaction, and QOL both physically and mentally, and decreased levels of anxiety and depression over time. And spousal caregivers showed greater improvement in marital satisfaction and physical QOL compared with patients. In addition, significant intervention effects were shown in the participants' benefit finding, physical health and depressive symptoms.ConclusionThe study confirmed the effect of the PTG intervention on CRC couples' benefit finding, physical health and depressive symptoms. However, this study only measured outcome variables at two time‐points. Future studies should add follow‐up assessments to evaluate long‐term effects of the intervention in CRC couples.Registration numberChiCTR2300067809.

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基于夫妇的创伤后成长干预在支持夫妇应对结直肠癌方面的效果：一项随机对照研究

目的为了促进结直肠癌（CRC）夫妇的创伤后成长（PTG），进行了基于夫妇的PTG干预，并且该干预先前被证明在CRC夫妇中是可行的。目前的研究旨在验证干预措施对 CRC 夫妇的效果。方法这是一项随机对照研究，纳入了 174 对 CRC 夫妇。所有参与者被随机分配接受干预（常规护理加 5 周 PTG 干预，n= 87）或对照组（常规护理，n= 87）。数据是在基线和干预后立即从 CRC 夫妇组中收集的。主要结果是指积极的变化，次要结果包括婚姻满意度、生活质量（QOL）以及焦虑和抑郁。应用多层次模型分析干预效果。结果随着时间的推移，项目参与者的PTG、婚姻满意度和身心生活质量均有所提高，焦虑和抑郁水平有所下降。与患者相比，配偶照顾者在婚姻满意度和身体生活质量方面表现出更大的改善。此外，在参与者的获益发现、身体健康和抑郁症状方面也显示出显着的干预效果。结论该研究证实了PTG干预对CRC夫妇的获益发现、身体健康和抑郁症状的影响。然而，这项研究仅测量了两个时间点的结果变量。未来的研究应增加随访评估，以评估干预措施对 CRC 夫妇的长期影响。注册号 ChiCTR2300067809。