Theaflavins (TFs) are a kind of bioactive compound that formed during the fermentation stage of black tea. TFs play a vital role both in the sensory quality and the biological activity of black tea. However, the complex composition of black tea and the low content of TFs in black tea (0.3%–0.7%) make the technology for the preparation of high-purity TFs a great challenge. This review provides an updated overview for extracting, synthesizing and purifying of TFs. Molecular imprinting technology, an efficient method for extracting bioactive compounds, will be a promising method for the preparation of TFs with high purity. Overall, this review can provide a scientific basis and technical support for the preparation of TFs with high purity and will be helpful for the in-depth development and further research of TFs.

中文翻译：

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茶黄素制备最新进展：《合成、提取与纯化》

茶黄素（TF）是红茶发酵过程中形成的一种生物活性化合物。转录因子对红茶的感官品质和生物活性都起着至关重要的作用。然而，红茶成分复杂，且红茶中转录因子含量较低（0.3%~0.7%），使得高纯度转录因子的制备技术面临巨大挑战。本综述提供了转录因子的提取、合成和纯化的最新概述。分子印迹技术是一种提取生物活性化合物的有效方法，将成为制备高纯度转录因子的一种有前途的方法。总体而言，本综述可为高纯度TF的制备提供科学依据和技术支撑，有助于TF的深入开发和进一步研究。