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Correction: Cardiorenal effectiveness of empagliflozin vs. glucagon-like peptide-1 receptor agonists: final-year results from the EMPRISE study
Cardiovascular Diabetology ( IF 9.3 ) Pub Date : 2024-03-18 , DOI: 10.1186/s12933-024-02190-6
Phyo T. Htoo , Helen Tesfaye , Sebastian Schneeweiss , Deborah J. Wexler , Brendan M. Everett , Robert J. Glynn , Niklas Schmedt , Lisette Koeneman , Anouk Déruaz-Luyet , Julie M. Paik , Elisabetta Patorno

Correction: Cardiovascular Diabetology (2024) 23:57 https://doi.org/10.1186/s12933-024-02150-0

Following publication of the original article [1], the authors noticed an error in the hazard ratio (HR) for the hospitalization for heart failure (HHF) outcome in the abstract. The numbers in the other parts of the manuscript and the tables were correct.

In abstract section, the correct sentence should read “Compared with GLP-1RA, empagliflozin was associated with similar risks of MI or stroke [HR: 0.99 (0.92, 1.07); RD: − 0.23 (− 1.25, 0.79)], and lower risks of HHF [HR: 0.69 (0.62, 0.77); RD: − 2.28 (− 2.98, − 1.59)], MACE [HR: 0.90 (0.82, 0.99); RD: − 2.54 (− 4.76, − 0.32)], cardiovascular mortality or HHF [HR: 0.77 (0.69, 0.86); RD: − 4.11 (− 5.95, − 2.29)], and ESKD [0.75 (0.60, 0.94); RD: − 6.77 (− 11.97, − 1.61)].”

Figure 3 was also cut off on the right side with some columns missing which has now been corrected (Fig. 3).

Fig. 3
figure 3

Subgroup analyses for primary outcomes by age and sex. CAPTION: On the relative scale, empagliflozin was associated with a lower risk of MI/stroke in patients 65 years or older, while it was not associated with MI/stroke in patients younger than 65 years. The HR estimates were consistent across other subgroups for all outcomes. For all outcomes, RD estimates were larger in older than in younger patients, while they did not differ by sex

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  1. Htoo PT, Tesfaye H, Schneeweiss S, Wexler DJ, Everett BM, Glynn RJ, Schmedt N, Koeneman L, Déruaz-Luyet A, Paik JM, Patorno E. Cardiorenal effectiveness of empagliflozin vs. glucagon-like peptide-1 receptor agonists: final-year results from the EMPRISE study. Cardiovasc Diabetol. 2024;23(1):57. https://doi.org/10.1186/s12933-024-02150-0.

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Authors and Affiliations

  1. Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA

    Phyo T. Htoo, Helen Tesfaye, Sebastian Schneeweiss, Robert J. Glynn, Julie M. Paik & Elisabetta Patorno

  2. Massachusetts General Hospital Diabetes Center, Harvard Medical School, Boston, USA

    Deborah J. Wexler

  3. Divisions of Cardiovascular and Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, USA

    Brendan M. Everett

  4. Global Epidemiology, Boehringer Ingelheim International GmbH (Germany) DE, Berlin, Germany

    Niklas Schmedt & Anouk Déruaz-Luyet

  5. Global Medical Affairs, Lilly Deutschland GmbH, Bad Homburg, Germany

    Lisette Koeneman

  6. Division of Renal (Kidney) Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    Julie M. Paik

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Corresponding author

Correspondence to Elisabetta Patorno.

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Htoo, P.T., Tesfaye, H., Schneeweiss, S. et al. Correction: Cardiorenal effectiveness of empagliflozin vs. glucagon-like peptide-1 receptor agonists: final-year results from the EMPRISE study. Cardiovasc Diabetol 23, 103 (2024). https://doi.org/10.1186/s12933-024-02190-6

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中文翻译:

更正:恩格列净与胰高血糖素样肽 1 受体激动剂的心肾功效:EMPRISE 研究的最终结果

更正:心血管糖尿病学(2024)23:57 https://doi.org/10.1186/s12933-024-02150-0

原始文章 [1] 发表后,作者注意到摘要中心力衰竭 (HHF) 住院结果的风险比 (HR) 存在错误。手稿其他部分和表格中的数字是正确的。

在摘要部分,正确的句子应为“与 GLP-1RA 相比,恩格列净与 MI 或中风的相似风险相关[HR: 0.99 (0.92, 1.07);RD:− 0.23 (− 1.25, 0.79)],HHF 风险较低[HR:0.69 (0.62, 0.77);RD:- 2.28(- 2.98,- 1.59)],MACE [HR:0.90(0.82,0.99);RD:− 2.54 (− 4.76,− 0.32)],心血管死亡率或 HHF [HR:0.77 (0.69,0.86);RD:− 4.11 (− 5.95,− 2.29)],ESKD [0.75 (0.60,0.94);RD:- 6.77 (- 11.97,- 1.61)]。”

图 3 的右侧也被截断,缺少一些列,现已更正(图 3)。

图3
图3

按年龄和性别对主要结局进行亚组分析。图片说明:在相对范围内,恩格列净与 65 岁或以上患者的 MI/中风风险较低相关,而与 65 岁以下患者的 MI/中风风险无关。对于所有结果,其他亚组的 HR 估计都是一致的。对于所有结果,老年患者的 RD 估计值大于年轻患者,但它们在性别上没有差异

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  1. Htoo PT、Tesfaye H、Schneeweiss S、Wexler DJ、Everett BM、Glynn RJ、Schmedt N、Koeneman L、Déruaz-Luyet A、Paik JM、Patorno E。恩格列净与胰高血糖素样肽 1 受体激动剂的心肾功效: EMPRISE 研究的最终结果。心血管糖尿病。2024;23(1):57。https://doi.org/10.1186/s12933-024-02150-0。

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  1. 布莱根妇女医院和哈佛医学院医学部药物流行病学和药物经济学部,1620 Tremont Street, Suite 3030, Boston, MA, 02120, USA

    Phyo T. Htoo、Helen Tesfaye、Sebastian Schneeweiss、Robert J. Glynn、Julie M. Paik 和 Elisabetta Patorno

  2. 马萨诸塞州总医院糖尿病中心,哈佛医学院,波士顿,美国

    黛博拉·韦克斯勒

  3. 哈佛医学院布莱根妇女医院医学系心血管和预防医学科,75 Francis Street,波士顿,马萨诸塞州,美国

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Htoo, PT、Tesfaye, H.、Schneeweiss, S.等人。更正:恩格列净与胰高血糖素样肽 1 受体激动剂的心肾功效:EMPRISE 研究的最后一年结果。心血管糖尿病 23 , 103 (2024)。https://doi.org/10.1186/s12933-024-02190-6

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