Ambulatory blood pressure after 12 weeks of quadruple combination of quarter doses of blood pressure medication vs. standard medication.,Journal of Hypertension

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Ambulatory blood pressure after 12 weeks of quadruple combination of quarter doses of blood pressure medication vs. standard medication.
Journal of Hypertension ( IF 4.9 ) Pub Date : 2024-02-29 , DOI: 10.1097/hjh.0000000000003683
Janis M. Nolde ₁ , Emily Atkins _{2,

3,

4} , Simone Marschner _{3,

4} , Graham S. Hillis _{5,

6} , John Chalmers ₂ , Laurent Billiot ₂ , Mark R. Nelson ₇ , Christopher M. Reid ₈ , Peter Hay ₉ , Michael Burke ₁₀ , Shirley Jansen ₁₁ , Tim Usherwood _{2,

3,

4} , Anthony Rodgers ₂ , Clara K. Chow _{2,

3,

4} , Markus P. Schlaich _{1,

5,

6,

12}

Affiliation

Dobney Hypertension Centre, Medical School - Royal Perth Hospital Unit, The University of Western Australia, Perth, Western Australia
The George Institute for Global Health, University of New South Wales
Westmead Applied Research Centre, University of Sydney
Department of Cardiology, Westmead Hospital, Sydney, New South Wales
Department of Cardiology, Royal Perth Hospital
School of Medicine, The University of Western Australia, Perth, Western Australia
Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania
School of Public Health & Preventive Medicine Monash University, School of Population Health, Curtin University, Perth, Western Australia
Castle Hill Medical Centre Sydney
School of Medicine, Western Sydney University, Sydney, New South Wales
Sir Charles Gairdner Hospital, Perth, Western Australia
Neurovascular Hypertension & Kidney Disease Laboratory, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

A combination of four ultra-low-dose blood pressure (BP) medications lowered office BP more effectively than initial monotherapy in the QUARTET trial. The effects on average ambulatory BP changes at 12 weeks have not yet been reported in detail.

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