New-onset postoperative atrial fibrillation (POAF) after coronary artery bypass surgery (CABG) occurs with an incidence of 20–40%. The clinical relevance of POAF remains a concern, and the need for further studies regarding the clinical management of POAF is necessary. The AFRODITE study, a prospective multicenter cohort study, had as its primary endpoint the evaluation of AF recurrence in patients post CABG over a one-year period. Two hundred twenty-eight patients aged >50 years who underwent isolated CABG were included in the study. Patients were stratified into two groups, POAF and non-POAF, and followed for 12 months for AF recurrence, hospitalizations, and death. Two hundred twenty-eight patients (mean age 67 years, 88.6% male) were included in the study. 28.5% of patients experienced at least one episode of POAF during index hospitalization (POAF group) and were compared with the non-POAF group (n = 163). Multivariate stepwise logistic regression analysis showed that the strongest prognostic parameter for POAF was the CHADS-Vasc score (odds ratio = 1.61, p < 0.001). POAF patients had a worse in-hospital outcome, but the incidence of long-term AF recurrence was not statistically different (3.6% vs. 4.8%, p = 0.9). Interestingly, a one-year prospective follow-up of patients in the study did not reveal significant differences between POAF and non-POAF patients. A notable finding was that patients with a higher CHADS-Vasc score were more likely to develop POAF.

中文翻译：

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CABG 后心房颤动和心律失常复发的风险：AFRODITE 研究

冠状动脉搭桥手术 (CABG) 后新发术后心房颤动 (POAF) 的发生率为 20-40%。POAF 的临床相关性仍然令人担忧，有必要对 POAF 的临床管理进行进一步研究。AFRODITE 研究是一项前瞻性多中心队列研究，其主要终点是评估患者在 CABG 后一年内的 AF 复发情况。该研究纳入了 228 名年龄 > 50 岁且接受孤立 CABG 的患者。患者被分为两组：POAF 和非 POAF，并随访 12 个月的 AF 复发、住院和死亡情况。该研究纳入了 228 名患者（平均年龄 67 岁，88.6% 为男性）。28.5% 的患者在首次住院期间至少经历过一次 POAF（POAF 组），并将其与非 POAF 组进行比较（n = 163）。多变量逐步逻辑回归分析显示，POAF 最强的预后参数是 CHADS-Vasc 评分（比值比 = 1.61，p < 0.001）。POAF 患者的院内结局较差，但长期 AF 复发的发生率没有统计学差异（3.6% vs. 4.8%，p = 0.9）。有趣的是，该研究中对患者进行的一年前瞻性随访并未显示 POAF 和非 POAF 患者之间存在显着差异。一个值得注意的发现是，CHADS-Vasc 评分较高的患者更有可能发生 POAF。