Postexercise blood pressure (BP) may be a better predictor of cardiovascular risk than office BP, but there is a lack of data supporting this claim. We hypothesized that postexercise BP may be an important prognostic marker. Our aim was to evaluate the association of postexercise BP with major adverse cardiovascular events (MACE) and all‐cause mortality. A total of 2581 participants (median age, 46 years; 55.9% women) from the Coronary Artery Risk Development in Young Adults study at year 20 (2005–2006) who underwent a graded exercise treadmill test using a modified Balke graded protocol were included. Postexercise BP was measured at baseline. Cox models were used to estimate the associations of postexercise BP with MACE and all‐cause mortality. Participants were followed up until December 31, 2021. In the entire population, postexercise systolic BP showed no significant association with MACE or all‐cause mortality, while postexercise diastolic BP was associated with MACE (hazard ratios [HR], 1.27 [95% CI, 1.06–1.52], per 10 mmHg increase) and all‐cause mortality (HR, 1.26 [95% CI, 1.05–1.51], per 10 mmHg increase). In the normal BP group, postexercise systolic BP was not significantly associated with MACE or all‐cause mortality, and postexercise diastolic BP was strongly associated with MACE (HR, 1.57 [95% CI, 1.18–2.09], per 10 mmHg increase). In this population‐based cohort study, postexercise diastolic BP was significantly associated with the risk of MACE and all‐cause mortality. Among individuals with normal BP, postexercise diastolic BP could identify those at a higher risk of cardiovascular events.

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运动后血压与心血管结局和死亡率的关联：CARDIA 研究

运动后血压 (BP) 可能比诊室血压更好地预测心血管风险，但缺乏支持这一说法的数据。我们假设运动后血压可能是一个重要的预后标志。我们的目的是评估运动后血压与主要不良心血管事件 (MACE) 和全因死亡率的关系。共有 2581 名来自年轻人冠状动脉风险发展研究（2005-2006）的 20 岁参与者（中位年龄 46 岁；55.9% 为女性）纳入其中，他们使用修改后的 Balke 分级方案进行了分级运动跑步机测试。在基线时测量运动后血压。 Cox 模型用于估计运动后血压与 MACE 和全因死亡率的关联。对参与者进行随访直至 2021 年 12 月 31 日。在整个人群中，运动后收缩压与 MACE 或全因死亡率没有显着相关性，而运动后舒张压与 MACE 相关（风险比 [HR]，1.27 [95% CI ，1.06–1.52]，每增加 10 mmHg）和全因死亡率（HR，1.26 [95% CI，1.05–1.51]，每增加 10 mmHg）。在正常血压组中，运动后收缩压与 MACE 或全因死亡率没有显着相关性，而运动后舒张压与 MACE 密切相关（HR，1.57 [95% CI，1.18-2.09]，每增加 10 mmHg）。在这项基于人群的队列研究中，运动后舒张压与 MACE 和全因死亡率风险显着相关。在血压正常的个体中，运动后舒张压可以识别心血管事件风险较高的个体。