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Factors associated with recurrence in patients with oral cancer in Mongolia
BMC Cancer ( IF 3.8 ) Pub Date : 2024-03-20 , DOI: 10.1186/s12885-024-12118-8
Oyuntsetseg Davaatsend , Munkhdul Altannamar , Mandukhai Ganbat , Urjinlkham Jagdagsuren

In Mongolia, there has been limited research on the posttreatment survival rate, recurrence, and occurrence of oral cancer. The goal of this study is to investigate the risk factors that contribute to the recurrence of oral cancer to increase survival rates, facilitate early detection, and improve treatment accuracy. A retrospective cohort method was used, with medical records from 173 patients diagnosed with squamous cell carcinoma of the mouth at the National Cancer Center of Mongolia’s Department of Head and Neck Surgery, Radio, and Chemotherapy between 2012 and 2017. The Mongolian National University of Medical Sciences’ Research Ethics Committee approved the project. The findings revealed that 109 cases (63.0%) were men and 64 (37.0%) were females, with a large proportion of patients (28.3%) falling between the ages of 61 and 70. Men had a 3.8 times higher risk of cancer recurrence than women (OR = 3.79, CI = 1.24–11.57). Furthermore, lymph node metastases and treatment were linked to oral cancer recurrence. This study offers light on the factors that influence the recurrence of oral cancer, giving useful insights for improving patient outcomes through early detection and proper treatment.

中文翻译:

蒙古口腔癌患者复发的相关因素

在蒙古,关于口腔癌治疗后生存率、复发和发生率的研究有限。本研究的目的是调查导致口腔癌复发的危险因素,以提高生存率、促进早期发现并提高治疗准确性。采用回顾性队列方法,收集了 2012 年至 2017 年间蒙古国家癌症中心头颈外科、放射和化疗科诊断为口腔鳞状细胞癌的 173 例患者的病历。 蒙古国立医科大学科学研究伦理委员会批准了该项目。结果显示,109例(63.0%)为男性,64例(37.0%)为女性,其中很大一部分患者(28.3%)年龄在61岁至70岁之间。男性的癌症复发风险是男性的3.8倍高于女性(OR = 3.79,CI = 1.24–11.57)。此外,淋巴结转移和治疗与口腔癌复发有关。这项研究揭示了影响口腔癌复发的因素,为通过早期检测和适当治疗改善患者预后提供了有用的见解。
更新日期:2024-03-20
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