Cannabis, traditionally used for recreation due to psychoactive compounds in its leaves, flowers, and seeds, has not been thoroughly explored for potential therapeutic benefits. Δ9-trans-Tetrahydrocannabinol, a key cannabinoid in cannabis, causes hallucinogenic effects and delirium symptoms. In contrast, cannabidiol (CBD) does not induce hallucinations and has shown effectiveness in treating symptoms of various rare, incurable diseases. Cannabis exhibits neuroprotective, anti-inflammatory, anti-thrombotic, anti-bacterial, analgesic, and antiepileptic properties, recently attracting more attention. This review aims to summarize comprehensively the impact of cannabis on human health, focusing on endocannabinoids and their receptors. It also delves into recent CBD research advancements, highlighting the compound’s potential medical applications. Overall, this paper provides valuable insights into the prospective development of medical cannabis, with a particular emphasis on CBD.

中文翻译：

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大麻中大麻二酚的有益作用

大麻传统上用于娱乐，因为其叶子、花和种子中含有精神活性化合物，但尚未对其潜在的治疗益处进行彻底探索。Δ9-反式四氢大麻酚是大麻中的一种关键大麻素，会引起致幻作用和谵妄症状。相比之下，大麻二酚（CBD）不会引起幻觉，并且在治疗各种罕见、不治之症的症状方面显示出有效性。大麻具有神经保护、抗炎、抗血栓、抗菌、镇痛和抗癫痫等特性，最近引起了越来越多的关注。本综述旨在全面总结大麻对人类健康的影响，重点关注内源性大麻素及其受体。它还深入研究了最近的 CBD 研究进展，强调了该化合物潜在的医疗应用。总的来说，本文为医用大麻的未来发展提供了宝贵的见解，特别强调了 CBD。