There is an escalating trend in both the incidence and prevalence of atrial fibrillation (AF). AF is linked to numerous other comorbidities, contributing to the emergence of multimorbidity. The sustained rise in multimorbidity and AF prevalences exerts a significant strain on healthcare systems globally. The understanding of the relation between multimorbidity and AF is essential to determine effective healthcare strategies, improve patient outcomes to adequately address the burden of AF. It not only begins with the accurate identification of comorbidities in the setting of AF. There is also the need to understand the pathophysiology of the different comorbidities and their common interactions, and how multimorbidity influences AF perpetuation. To manage the challenges that rise from the increasing incidence and prevalence of both multimorbidity and AF, such as adverse events and hospitalisations, the treatment of comorbidities in AF has already gained importance and will need to be a primary focus in the forthcoming years. There are numerous challenges to overcome in the treatment of multimorbidity in AF, whereby the identification of comorbidities is essential. Integrated care strategies focused on a comprehensive multimorbidity management with an individual-centred approach need to be determined to improve healthcare strategies and reduce the AF-related risk of frailty, cardiovascular diseases and improve patient outcomes. No data are available.

中文翻译：

---

房颤患者的多重病态

心房颤动（AF）的发病率和患病率均呈上升趋势。房颤与许多其他合并症有关，导致多种疾病的出现。多种疾病和房颤患病率的持续上升给全球医疗保健系统带来了巨大压力。了解多发病和房颤之间的关系对于确定有效的医疗策略、改善患者的治疗结果以充分解决房颤的负担至关重要。它不仅始于准确识别 AF 背景下的合并症。还需要了解不同合并症的病理生理学及其常见的相互作用，以及多重疾病如何影响房颤的持续存在。为了应对多发病和房颤发病率和患病率不断增加所带来的挑战，例如不良事件和住院治疗，房颤合并症的治疗已经变得越来越重要，并且需要成为未来几年的主要重点。治疗 AF 的多种疾病需要克服许多挑战，因此识别合并症至关重要。需要确定以个体为中心的综合治疗策略，以全面的多发病管理为重点，以改善医疗保健策略，降低房颤相关的虚弱、心血管疾病风险，并改善患者的治疗结果。无可用数据。