Poly(vinyl alcohol) (PVA) is an attractive raw material and widely applicated in multiple fields owing to its unique features. However, the poor mechanical strength and without intrinsic antimicrobial activity severely restrained its further use. Herein, we proposed a novel strategy to fabricate PVA-based composites film with excellent mechanical properties and superior antibacterial activity by employing functional polymeric microspheres as a hydrogen bonding cross-linker and bactericide loading platform. Firstly, we synthesized poly(maleic anhydride--vinyl chloride) cross-linked microspheres (PDVM) self-stabilized precipitation polymerization and subsequently the PDVM microspheres were reacted with gaseous ammonia to endow the microsphere surface with abundant carboxyl and amidogen group. As a result, uniform PDVM microspheres with diameters ranging from 175 to 685 nm and controlled gel content (25.3–91.8%) were prepared successfully and aminolyzed PDVM microsphere (NPDVM) were obtained. By incorporating 5 wt% NPDVM in PVA matrix, the composite film has a significant increment in tensile strength (63.9 MPa) and elongation at break (107 %) in comparison to neat PVA (51.8 MPa, 80%) mainly attributed to the formation of multiple hydrogen bonding network. Furthermore, by immobilizing Zn on the surface of NPDVM/PVA film complexation, the composite film exhibited outstanding antibacterial efficiency against and .

中文翻译：

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聚马来酸酐-氯乙烯交联微球的合成及其对聚乙烯醇复合薄膜机械强度和抗菌活性的优异增强

聚乙烯醇（PVA）是一种极具吸引力的原材料，因其独特的性能而广泛应用于多个领域。然而机械强度差且缺乏内在的抗菌活性严重限制了其进一步的使用。在此，我们提出了一种新策略，通过采用功能性聚合物微球作为氢键交联剂和杀菌剂负载平台来制备具有优异机械性能和优异抗菌活性的PVA基复合膜。首先，我们采用自稳定沉淀聚合法合成了聚马来酸酐--氯乙烯交联微球（PDVM），随后将PDVM微球与气态氨反应，赋予微球表面丰富的羧基和氨基基团。结果，成功制备了直径为175至685 nm、凝胶含量受控（25.3%至91.8%）的均匀PDVM微球，并获得了氨解的PDVM微球（NPDVM）。通过在 PVA 基体中加入 5 wt% NPDVM，与纯 PVA（51.8 MPa，80%）相比，复合膜的拉伸强度（63.9 MPa）和断裂伸长率（107%）显着增加，这主要归因于形成多个氢键网络。此外，通过将Zn固定在NPDVM/PVA薄膜络合表面，复合薄膜对 和 表现出优异的抗菌效率。