The impact of methylparaben on human and ecosystem health has been controversial since this synthetic preservative was introduced to the industry in the 1930s. At first, it was considered that this phenolic compound was safe, but recent studies have proven that this claim might not be valid. Though more investigations need to be carried out regarding this subject, the assessment of this chemical substance, which has been labeled as estrogen, an endocrine disruptor, and a potential carcinogen, is of great importance. Electrochemical platforms have been demonstrated as reliable and cost-worthy methods to quantify methylparaben in different media compared to expensive conventional strategies owing to their unique features, such as simplicity, short response time, and high precision. Through the past two decades, various arrays of conductive materials on the nanoscale, such as carbon nanomaterials, metal nanoparticles, metal oxide nanostructures, nanocomposites, and even biological molecules, have been utilized to enhance the precision and selectivity of methylparaben electrochemical platforms. This work presents a comparative study of different types of electrochemical strategies employed in methylparaben detection and quantification. Moreover, current challenges limiting the applicability of the developed platforms are discussed, and future perspective of the research in this field is outlined.

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对羟基苯甲酸甲酯分析的电化学传感策略概述

自 20 世纪 30 年代将这种合成防腐剂引入该行业以来，尼泊金甲酯对人类和生态系统健康的影响一直存在争议。起初，人们认为这种酚类化合物是安全的，但最近的研究证明这种说法可能并不成立。尽管还需要对这一主题进行更多研究，但对这种被标记为雌激素、内分泌干扰物和潜在致癌物的化学物质的评估非常重要。与昂贵的传统策略相比，电化学平台已被证明是量化不同介质中对羟基苯甲酸甲酯的可靠且经济的方法，因为其具有简单、响应时间短和高精度等独特的特点。在过去的二十年中，各种纳米级导电材料阵列，如碳纳米材料、金属纳米颗粒、金属氧化物纳米结构、纳米复合材料，甚至生物分子，已被用来提高对羟基苯甲酸甲酯电化学平台的精度和选择性。这项工作对尼泊金甲酯检测和定量中采用的不同类型的电化学策略进行了比较研究。此外，还讨论了当前限制所开发平台的适用性的挑战，并概述了该领域研究的未来前景。