Listeriosis is a foodborne infection in humans caused by Listeria monocytogenes. Consumption of contaminated food can lead to severe infection in vulnerable patients, that can be fatal. Clinical manifestations include sepsis and meningitis, and in pregnancy-associated infection, miscarriage and stillbirth. Diagnosis is confirmed by culture and identification of the pathogen from blood, cerebrospinal fluid, vaginal swab, placenta or amniotic fluid. Treatment regimens recommend amoxicillin, ampicillin or an aminoglycoside. Virulence factors mediate bacterial adhesion and invasion of gut epithelial cells. Other factors mediate biofilm formation and tolerance to low temperatures and high salt concentrations facilitating persistence and survival in the environment.

中文翻译：

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单增李斯特菌：沉默的杀手

李斯特菌病是由单核细胞增生李斯特菌引起的人类食源性感染。食用受污染的食物可能会导致脆弱患者严重感染，甚至致命。临床表现包括败血症和脑膜炎，以及妊娠相关感染、流产和死产。通过血液、脑脊液、阴道拭子、胎盘或羊水中的病原体培养和鉴定来确诊。治疗方案推荐使用阿莫西林、氨苄西林或氨基糖苷类药物。毒力因子介导细菌粘附和侵袭肠上皮细胞。其他因素介导生物膜的形成以及对低温和高盐浓度的耐受性，从而促进在环境中的持久性和生存。