Dengue virus, primarily transmitted by the Aedes aegypti mosquito, is a major public health concern affecting ≈3.83 billion people worldwide. Recent releases of Wolbachia-transinfected Ae. aegypti in several cities worldwide have shown that it can reduce dengue transmission. However, these releases are costly, and, to date, no framework has been proposed for determining economically optimal release strategies that account for both costs associated with disease risk and releases.

中文翻译：

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释放感染沃尔巴克氏体的埃及伊蚊以预防登革热的经济优化

登革热病毒主要由埃及伊蚊传播，是影响全球约 38.3 亿人的主要公共卫生问题。最近释放的沃尔巴克氏体转染的伊蚊。全球多个城市的埃及伊蚊已表明它可以减少登革热传播。然而，这些释放成本高昂，并且迄今为止，尚未提出框架来确定经济上最佳的释放策略，以考虑与疾病风险和释放相关的成本。