Yongyu Zhang, Shiji Wang, Zhongmin Liu, Lewei Yang, Jian Liu, Ming Xiu. Increased Six1 expression in macrophages promotes hepatocellular carcinoma growth and invasion by regulating MMP‐9. J Cell Mol Med. 2019; 23: 4523–4533. https://doi.org/10.1111/jcmm.14342.The above article, published online on 02 May 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor‐in‐Chief, Stefan Constantinescu, The Foundation for Cellular and Molecular Medicine and John Wiley and Sons Ltd. The authors asked to retract the article as they found that the experiments presented were not reproducible, due to a possible cell line contamination, and therefore the conclusions of the paper are not supported. Subsequently, an investigation into concerns raised by a third party revealed inappropriate duplication of images within the article (Figure 2C,D subpanels) as well as between this (Figure 2B subpanels) and four other articles that were previously published in a different scientific context. Thus, the editors consider the conclusions of this manuscript substantially compromised. Although the authors initially asked for the retraction, when asked to approve the retraction wording, they remained unresponsive.

中文翻译：

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撤回：巨噬细胞中 Six1 表达增加通过调节 MMP-9 促进肝细胞癌生长和侵袭

张永宇，王世吉，刘忠民，杨乐伟，刘健，秀明。巨噬细胞中 Six1 表达增加通过调节 MMP-9 促进肝细胞癌生长和侵袭。细胞分子医学杂志。 2019； 23：4523–4533。https://doi.org/10.1111/jcmm.14342.上述文章于 2019 年 5 月 2 日在线发表于 Wiley Online Library (wileyonlinelibrary.com），经作者、期刊主编 Stefan Constantinescu、细胞与分子医学基金会和 John Wiley and Sons Ltd 同意撤回。作者要求撤回该文章，因为他们发现所提出的实验由于可能存在细胞系污染，无法重现，因此该论文的结论不受支持。随后，对第三方提出的担忧进行的调查显示，该文章（图 2C、D 子面板）以及该文章（图 2B 子面板）与之前在不同科学背景下发表的其他四篇文章之间存在图像不适当的重复。因此，编辑认为这篇手稿的结论受到了严重损害。尽管作者最初要求撤回，但当被要求批准撤回措辞时，他们仍然没有回应。