The unique physical and biological characteristics of proton and carbon ions allow for improved sparing of normal tissues, decreased integral dose to the body, and increased biological effect through high linear energy transfer. These properties are particularly useful for sarcomas given their histology, wide array of locations, and age of diagnosis. This review summarizes the literature and describes the clinical situations in which these heavy particles have advantages for treating sarcomas.

中文翻译：

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使用质子和碳离子放射疗法治疗肉瘤

质子和碳离子独特的物理和生物特性可以改善正常组织的保护，减少对身体的整体剂量，并通过高线性能量转移增加生物效应。鉴于其组织学、广泛的位置和诊断年龄，这些特性对于肉瘤特别有用。本综述总结了文献并描述了这些重颗粒具有治疗肉瘤优势的临床情况。