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A Simple Cost‐Effective Method to Fabricate Single Nanochannels by Embedding Electrospun Polyethylene Oxide Nanofibers
ChemistryOpen ( IF 2.3 ) Pub Date : 2024-03-21 , DOI: 10.1002/open.202400008
Lei Zhou 1, 2 , Zhuonan Chen 3 , Jian Ma 3, 4, 5
Affiliation  

Solid state nanochannels provide significant practical advantages in many fields due to their interesting properties, such as controllable shape and size, robustness, ion selectivity. But their complex preparation processes severely limit their application. In this study, a simple cost‐effective method to fabricate single nanochannel by embedding a single polyethylene oxide (PEO) nanofiber is presented. Firstly, PEO nanofibers are prepared by electrospinning, and then a single PEO nanofiber are precisely transferred to the target sample using a micromanipulation platform. Then, PDMS is used for embedding, and finally, the PEO nanofiber is dissolved to obtain a single nanochannel. Unlike other methods of preparing nanochannels by embedding nanofibers, this method can prepare single nanochannel. The diameter of nanochannel can be as fine as 100 nm, and the length can reach several micrometers. The power generation between two potassium chloride solutions with various combinations of concentrations was investigated using the nanochannel. This low‐cost flexible nanochannel can also be used in various applications, including DNA sequencing and biomimetic ion channel.

中文翻译:

一种通过嵌入电纺聚环氧乙烷纳米纤维制造单纳米通道的简单且具有成本效益的方法

固态纳米通道由于其有趣的特性(例如可控形状和尺寸、鲁棒性、离子选择性)在许多领域提供了显着的实际优势。但其复杂的制备过程严重限制了其应用。在这项研究中,提出了一种通过嵌入单个聚环氧乙烷(PEO)纳米纤维来制造单个纳米通道的简单且经济有效的方法。首先,通过静电纺丝制备PEO纳米纤维,然后利用显微操作平台将单根PEO纳米纤维精确转移到目标样品上。然后用PDMS进行包埋,最后将PEO纳米纤维溶解得到单个纳米通道。与其他通过嵌入纳米纤维制备纳米通道的方法不同,该方法可以制备单个纳米通道。纳米通道的直径可细至100纳米,长度可达数微米。使用纳米通道研究了具有不同浓度组合的两种氯化钾溶液之间的发电。这种低成本的柔性纳米通道还可用于各种应用,包括 DNA 测序和仿生离子通道。
更新日期:2024-03-21
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