BackgroundTuberculosis remains the leading cause of death by an infectious disease among people living with HIV (PLHIV). TB Preventive Treatment (TPT) is a cost-effective intervention known to reduce morbidity and mortality. We used data from ZIMPHIA 2020 to assess TPT uptake and factors associated with its use.MethodologyZIMPHIA a cross-sectional household survey, estimated HIV treatment outcomes among PLHIV aged ≥15 years. Randomly selected participants provided demographic and clinical information. We applied multivariable logistic regression models using survey weights. Variances were estimated via the Jackknife series to determine factors associated with TPT uptake.ResultsThe sample of 2419 PLHIV ≥15 years had 65% females, 44% had no primary education, and 29% lived in urban centers. Overall, 38% had ever taken TPT, including 15% currently taking TPT. Controlling for other variables, those screened for TB at last HIV-related visit, those who visited a TB clinic in the previous 12 months, and those who had HIV viral load suppression were more likely to take TPT.ConclusionThe findings show suboptimal TPT coverage among PLHIV. There is a need for targeted interventions and policies to address the barriers to TPT uptake, to reduce TB morbidity and mortality among PLHIV.

中文翻译：

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人类免疫缺陷病毒感染者对结核病预防治疗的接受情况：2020 年津巴布韦基于人群的人类免疫缺陷病毒影响评估分析

背景结核病仍然是艾滋病毒感染者（PLHIV）感染者死亡的主要原因。结核病预防治疗（TPT）是一种具有成本效益的干预措施，已知可以降低发病率和死亡率。我们使用 ZIMPHIA 2020 的数据来评估 TPT 的吸收情况以及与其使用相关的因素。方法 ZIMPHIA 是一项横断面家庭调查，估计了年龄≥15 岁的 PLHIV 患者的 HIV 治疗结果。随机选择的参与者提供了人口统计和临床信息。我们使用调查权重应用多变量逻辑回归模型。通过 Jackknife 系列估计方差，以确定与 TPT 吸收相关的因素。结果 2419 名年龄≥15 岁的 PLHIV 样本中，65% 是女性，44% 没有接受过初等教育，29% 居住在城市中心。总体而言，38% 的人曾经接受过 TPT，其中 15% 的人目前正在接受 TPT。控制其他变量后，那些在最近一次与 HIV 相关的就诊中筛查过结核病的人、那些在过去 12 个月内访问过结核病诊所的人以及那些接受过 HIV 病毒载量抑制的人更有可能接受 TPT。 结论 研究结果显示，在艾滋病毒感染者。需要采取有针对性的干预措施和政策来解决接受 TPT 的障碍，以降低艾滋病毒感染者中的结核病发病率和死亡率。