In order to provide a long-lasting formulation for spinosad (SP) targeting larval stages of Aedes aegypti (Linnaeus) and others alike, a SP tablet was developed based on microspheres, using polylactic acid as inside coating material. The microspheres were encapsulated using polyethylene glycol and 1-hexadecanol to form a sustained-release SP tablet. Micromorphology, active ingredient loading, structure identification, photolysis resistance and biological activity were evaluated in this report.

中文翻译：

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多杀菌素微球长效片剂的制备及其对黄热病蚊、埃及伊蚊（双翅目：库蚊科）幼虫的残留杀虫功效

为了提供针对埃及伊蚊（Linnaeus）等幼虫期的多杀菌素（SP）长效制剂，开发了一种基于微球的 SP 片剂，使用聚乳酸作为内包衣材料。使用聚乙二醇和1-十六醇将微球封装形成缓释SP片剂。本报告评估了微观形态、活性成分负载、结构鉴定、光解抗性和生物活性。