Background & AimsChanges in stomach size may impact eating behaviour. A recent study showed gastric dilatation in restrictive eating disorders using computed tomography scans. This study aimed to describe stomach size in the standing position in women with anorexia nervosa (AN).MethodsWomen treated for AN at our institution were retrospectively included if they had undergone upper gastrointestinal radiography (UGR) after the diagnosis of AN. Two control groups (CG1 and CG2) were included, both comprising female patients: CG1 patients were not obese and underwent UGR for digestive symptoms of other aetiologies, and CG2 comprised obese individuals who had UGR before bariatric surgery. A UGR‐based Stomach Size Index (SSI), calculated as the ratio of the length of the stomach to the distance between the upper end of the stomach and the top of the iliac crests, was measured in all three groups. Gastromegaly was defined as SSI >1.00.Results45 patients suffering from AN (28 with restrictive and 17 with binge/purge subtype), 10 CG1 and 20 CG2 subjects were included in this study. Stomach Size Index was significantly higher in AN (1.27 ± 0.24) than in CG1 (0.80 ± 0.11) and CG2 (0.68 ± 0.09); p < 0.001, but was not significantly different between patients with the restrictive and binge/purge subtypes. Gastromegaly was present in 82.2% of patients with AN and not present in the control groups. In patients with AN, gastromegaly was present in 12/15 patients without digestive symptoms (80.0%) and in 25/30 patients with digestive complaints (83.3%) at time of UGR (p = 0.99). In the AN group, no significant relationship was found between SSI and body mass index.ConclusionGastromegaly is frequent in AN and could influence AN recovery. This anatomical modification could partially explain the alterations of gastric motility previously reported in AN.

中文翻译：

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神经性厌食症的胃大小：新挑战？

背景与目标胃大小的变化可能会影响饮食行为。最近的一项研究使用计算机断层扫描显示限制性饮食失调症的胃扩张。本研究旨在描述神经性厌食症 (AN) 女性站立时胃的大小。方法回顾性纳入在我们机构接受 AN 治疗的女性，如果她们在诊断 AN 后接受了上消化道 X 光检查 (UGR)。纳入两个对照组（CG1 和 CG2），均由女性患者组成：CG1 患者不肥胖，因其他病因的消化系统症状而接受 UGR，CG2 包括在减肥手术前患有 UGR 的肥胖个体。在所有三组中测量了基于 UGR 的胃尺寸指数 (SSI)，计算为胃长度与胃上端和髂嵴顶部之间的距离的比率。胃肿大定义为 SSI >1.00。结果 45 名患有 AN 的患者（28 名患有限制性的，17 名患有暴食/清除亚型）、10 名 CG1 和 20 名 CG2 受试者纳入本研究。 AN 中的胃尺寸指数 (1.27 ± 0.24) 显着高于 CG1 (0.80 ± 0.11) 和 CG2 (0.68 ± 0.09)；p< 0.001，但限制性亚型和暴食/清除亚型患者之间没有显着差异。 82.2% 的 AN 患者出现胃肿大，而对照组则不出现胃肿大。在 AN 患者中，12/15 名无消化系统症状的患者 (80.0%) 出现胃肿大，25/30 名患者在 UGR 时出现消化道症状 (83.3%)。p= 0.99）。在AN组中，SSI与体重指数之间没有发现显着关系。结论胃肿大在AN中很常见，并且可能影响AN的恢复。这种解剖学改变可以部分解释先前报道的 AN 中胃动力的改变。