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Testing pooled samples enables universal screening of congenital cytomegalovirus infection
Nature Medicine ( IF 82.9 ) Pub Date : 2024-03-21 , DOI: 10.1038/s41591-024-02901-2


The implementation of PCR tests of pooled saliva samples for universal screening of congenital cytomegalovirus infection was assessed in 15,805 neonates over 13 months. This extensive analysis revealed the high feasibility and empirical efficiency of the pooled testing approach, which had a clinically insignificant loss of sensitivity.

中文翻译:

测试混合样本可实现先天性巨细胞病毒感染的普遍筛查

在 13 个月内对 15,805 名新生儿进行了对汇集唾液样本进行 PCR 检测以普遍筛查先天性巨细胞病毒感染的评估。这项广泛的分析揭示了合并测试方法的高度可行性和经验效率,该方法的敏感性损失在临床上并不显着。
更新日期:2024-03-25
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