Abstract

Surface modification of titanium and its alloys has been seriously considered by researchers to improve their biological behaviors, in the past few decades. In present research, hydroxyapatite (HA) based composite coatings with different concentrations of 0, 2, 4, and 6 wt% of silver (Ag) nanoparticles were electrophoretically deposited (EPD) on anodized and non-anodized Ti6Al4V, using a direct current at a voltage of 30 V for 10 min at room temperature. The specimens were then characterized by means of X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) equipped with energy dispersive spectroscopy (EDS). The cell adhesion images and cell viability results showed that HA-Ag composite coatings significantly promoted the biocompatibility of samples compared with the non-anodized and anodized Ti6Al4V. The viabilities of Mg-63 cells on HA-4%Ag coating and bi-layer coating (HA-4%Ag on anodized specimen) were approximately 91% and they were considered as the best coatings in term of biocompatibility. On the other hand, the antibacterial assessments demonstrated that HA-6%Ag coating had the best antibacterial performance compared with other samples. Furthermore, Tafel polarization curves indicated that corrosion resistance of the bi-layer coating was higher than those of the other specimens. The polarization resistance of this coating was about 7 times more than that of theTi6Al4V alloy.

Graphical Abstract

中文翻译：

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纳米银对Ti6Al4V上电泳沉积羟基磷灰石薄膜生物和腐蚀行为的影响

摘要

在过去的几十年里，研究人员一直在认真考虑对钛及其合金进行表面改性，以改善其生物学行为。在目前的研究中，使用直流电在阳极氧化和非阳极氧化的 Ti6Al4V 上电泳沉积 (EPD) 不同浓度的银 (Ag) 纳米颗粒，其中羟基磷灰石 (HA) 基复合涂层具有不同浓度的 0、2、4 和 6 wt%。室温下30V电压10分钟。然后通过 X 射线衍射 (XRD) 分析、傅里叶变换红外光谱 (FT-IR)、配备能量色散光谱 (EDS) 的扫描电子显微镜 (SEM) 对样品进行表征。细胞粘附图像和细胞活力结果表明，与非阳极氧化和阳极氧化Ti6Al4V相比，HA-Ag复合涂层显着提高了样品的生物相容性。 Mg-63细胞在HA-4%Ag涂层和双层涂层（阳极氧化样品上的HA-4%Ag）上的存活率约为91%，它们被认为是生物相容性最好的涂层。另一方面，抗菌评估表明，与其他样品相比，HA-6%Ag涂层具有最佳的抗菌性能。此外，塔菲尔极化曲线表明双层涂层的耐腐蚀性能高于其他样品。该涂层的极化电阻比Ti6Al4V合金高约7倍。

图形概要