Biodegradable porous Mg scaffolds are a promising approach to bone repair. In this work, 3D-spherical porous Mg–1.5Zn–0.2Ca (wt.%) scaffolds were prepared by vacuum infiltration casting technology, and MgF₂ and fluorapatite coatings were designed to control the degradation behavior of Mg-based scaffolds. The results showed that the pores in Mg-based scaffolds were composed of the main spherical pores (450–600 μm) and interconnected pores (150–200 μm), and the porosity was up to 74.97%. Mg-based porous scaffolds exhibited sufficient mechanical properties with a compressive yield strength of about 4.04 MPa and elastic modulus of appropriately 0.23 GPa. Besides, both MgF₂ coating and fluorapatite coating could effectively improve the corrosion resistance of porous Mg-based scaffolds. In conclusion, this research would provide data support and theoretical guidance for the application of biodegradable porous Mg-based scaffolds in bone tissue engineering.

Graphical Abstract

中文翻译：

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用于骨修复的多孔镁锌钙支架：微观结构、力学性能和体外降解行为的研究

可生物降解的多孔镁支架是一种有前途的骨修复方法。在这项工作中，通过真空渗透铸造技术制备了3D球形多孔Mg–1.5Zn–0.2Ca（wt.%）支架，并设计了MgF ₂和氟磷灰石涂层来控制镁基支架的降解行为。结果表明，镁基支架的孔隙由主球形孔隙（450~600 μm）和连通孔隙（150~200 μm）组成，孔隙率高达74.97%。镁基多孔支架表现出足够的机械性能，压缩屈服强度约为4.04 MPa，弹性模量约为0.23 GPa。此外，MgF ₂涂层和氟磷灰石涂层均可有效提高多孔镁基支架的耐腐蚀性能。总之，本研究将为可生物降解多孔镁基支架在骨组织工程中的应用提供数据支持和理论指导。

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