Optical coherence tomography (OCT) is a noninvasive and label-free optical imaging system offering real-time visualization of morphological structures. The high costs associated with most existing commercial OCT systems have restricted their widespread availability, particularly in low-resource environments. Therefore, miniaturizing OCT devices holds the potential not only to reduce size but also to lower costs, opening up new markets for this technology. In this study, we developed single-board computer-based OCT (SBC-OCT) system, which was fabricated by 3-D printer. The total size of the developed SBC-OCT system is $230\times 230\times330$ mm3. To counter the thermal-induced alignment distortion of 3-D printed spectrometer during system operation, we developed an automatic signal compensation method applied temperature-insensitive (TI) spectrometer using an area-scan camera with no hardware modifications, no additional components, and minimal computational load. By comparing with conventional line-scan camera-based OCT during 90-min monitoring, the temperature variance robustness of the developed SBC-OCT effectively verified and successfully restored distorted images to their original quality. In addition, the applicability of our developed SBC-OCT system was demonstrated through cornea, retina, and fingerprint anti-spoofing imaging. The reduction in size, weight, and cost of SBC-OCT makes it highly relevant across medical, industrial, and security applications, demonstrating its potential for wide-ranging usage.

中文翻译：

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开发适用于多种应用的基于单板计算机的温度不敏感紧凑型光学相干断层扫描

光学相干断层扫描 (OCT) 是一种无创、无标记的光学成像系统，可提供形态结构的实时可视化。大多数现有商业 OCT 系统的高成本限制了它们的广泛可用性，特别是在资源匮乏的环境中。因此，小型化 OCT 设备不仅具有缩小尺寸的潜力，而且还具有降低成本的潜力，为该技术开辟了新的市场。在这项研究中，我们开发了基于单板计算机的 OCT (SBC-OCT) 系统，该系统由 3D 打印机制造。所开发的SBC-OCT系统的总规模为 $230\次230\次330$毫米3。为了应对系统运行期间 3D 打印光谱仪的热引起的对准失真，我们开发了一种自动信号补偿方法，该方法应用温度不敏感 (TI) 光谱仪，使用面扫描相机，无需修改硬件、无需额外组件，并且占用空间极小。计算负荷。通过与传统的基于线扫描相机的 OCT 在 90 分钟的监测过程中进行比较，所开发的 SBC-OCT 的温度变化鲁棒性有效验证并成功地将失真图像恢复到原始质量。此外，我们开发的SBC-OCT系统的适用性通过角膜、视网膜和指纹防欺骗成像得到了证明。 SBC-OCT 尺寸、重量和成本的减小使其在医疗、工业和安全应用中具有高度相关性，展示了其广泛使用的潜力。