Mechanistic insights into sodium ion-mediated ligand binding affinity and modulation of 5-HT2B GPCR activity: implications for drug discovery and development,Journal of Receptors and Signal Transduction

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Mechanistic insights into sodium ion-mediated ligand binding affinity and modulation of 5-HT2B GPCR activity: implications for drug discovery and development
Journal of Receptors and Signal Transduction ( IF 2.8 ) Pub Date : 2024-03-26 , DOI: 10.1080/10799893.2024.2332886
Arushi Chauhan ₁ , Jitender Singh ₁ , Namrata Sangwan ₁ , Pramod K. Avti ₁

Affiliation

The G-protein coupled receptor (GPCR) family, implicated in neurological disorders and drug targets, includes the sensitive serotonin receptor subtype, 5-HT2B. The influence of sodium ions on ligan...

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