Aspirin (AS) is a common drug having anti-pyretic and anti-inflammatory properties which is widely used in diverse medical conditions. The intake of AS may cause adverse effects such as gastrointestinal ulcer, tinnitus and Reye’s syndrome. The adverse effects of AS arise due to conversion of AS into salicylic acid (SAL). Glycine (Gly) is a simplest non essential amino acid having anti-oxidative and anti-inflammatory effects. It also reduces the risk of obesity, hypertension, and diabetes mellitus. AS with Gly is well accepted form of the drug for the treatment of rheumatic conditions in comparisons to the bare AS. In the present work using UV-Visible absorption, fluorescence and DFT/ TD-DFT techniques confirmed that in presence of Gly inhibited the conversion of AS into SAL effectively.

阿司匹林（AS）是一种具有解热和抗炎特性的常见药物，广泛用于多种医疗条件。摄入AS可能会引起胃肠道溃疡、耳鸣和雷氏综合症等不良反应。 AS 的不利影响是由于 AS 转化为水杨酸 (SAL) 所致。甘氨酸（Gly）是一种最简单的非必需氨基酸，具有抗氧化和抗炎作用。它还可以降低肥胖、高血压和糖尿病的风险。与单纯 AS 相比，含有 Gly 的 AS 是治疗风湿性疾病的广泛接受的药物形式。在目前的工作中，使用紫外-可见吸收、荧光和 DFT/TD-DFT 技术证实，Gly 的存在可以有效抑制 AS 转化为 SAL。