Sonodynamic therapy (SDT) is an emerging approach for malignant tumor treatment, offering high precision, deep tissue penetration, and minimal side effects. The rapid advancements in nanotechnology, particularly in cancer treatment, have enhanced the efficacy and targeting specificity of SDT. Combining sonodynamic therapy with nanotechnology offers a promising direction for future cancer treatments. In this review, we first systematically discussed the anti-tumor mechanism of SDT and then summarized the common nanotechnology-related sonosensitizers and their recent applications. Subsequently, nanotechnology-related therapies derived using the SDT mechanism were elaborated. Finally, the role of nanomaterials in SDT combined therapy was also introduced.

中文翻译：

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纳米技术支持的声动力治疗恶性肿瘤

声动力疗法（SDT）是一种新兴的恶性肿瘤治疗方法，具有高精度、深层组织穿透性和最小的副作用。纳米技术的快速进步，特别是在癌症治疗方面，提高了 SDT 的功效和靶向特异性。声动力疗法与纳米技术的结合为未来的癌症治疗提供了一个有希望的方向。在这篇综述中，我们首先系统地讨论了SDT的抗肿瘤机制，然后总结了常见的纳米技术相关的声敏剂及其近期应用。随后，利用SDT机制衍生的纳米技术相关疗法被详细阐述。最后还介绍了纳米材料在SDT联合治疗中的作用。