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Expression of the MSPDBL2 antigen in a discrete subset of Plasmodium falciparum schizonts is regulated by GDV1 but may not be linked to sexual commitment
mBio ( IF 6.4 ) Pub Date : 2024-03-26 , DOI: 10.1128/mbio.03140-23
Aline Freville 1 , Lindsay B. Stewart 1 , Kevin K. A. Tetteh 1 , Moritz Treeck 2 , Alfred Cortes 3, 4 , Till S. Voss 5, 6 , Sarah J. Tarr 1 , David A. Baker 1 , David J. Conway 1
Affiliation  

Malaria parasites in the blood are remarkably variable, able to switch antigenic targets so they may survive within humans who have already developed specific immune responses. This is one of the challenges in developing vaccines against malaria. MSPDBL2 ...

中文翻译:

恶性疟原虫裂殖体中 MSPDBL2 抗原的表达受 GDV1 调节,但可能与性承诺无关

血液中的疟疾寄生虫变化很大,能够转换抗原目标,因此它们可以在已经产生特异性免疫反应的人类体内生存。这是开发疟疾疫苗的挑战之一。 MSPDBL2 ...
更新日期:2024-03-27
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