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Carbon-based Nanomaterials in Photothermal Therapy Guided by Photoacoustic Imaging: State of Knowledge and Recent Advances
Current Medicinal Chemistry ( IF 4.1 ) Pub Date : 2024-03-26 , DOI: 10.2174/0109298673287448240311112523
Yan Xing 1 , Rui Jing 2 , Jun Kang 2 , Yuwen Li 2 , Hui Zhang 2 , Xiaoying Tang 2 , Zhenqi Jiang 2
Affiliation  

: Carbon-based nanomaterials (CBNM)have been widely used in various fields due to their excellent physicochemical properties. In particular, in the area of tumor diagnosis and treatment, researchers have frequently reported them for their potential fluorescence, photoacoustic (PA), and ultrasound imaging performance, as well as their photothermal, photodynamic, sonodynamic, and other therapeutic properties. As the functions of CBNM are increasingly developed, their excellent imaging properties and superior tumor treatment effects make them extremely promising theranostic agents. This review aims to integrate the considered and researched information in a specific field of this research topic and systematically present, summarize, and comment on the efforts made by authoritative scholars. In this review, we summarized the work exploring carbon-based materials in the field of tumor imaging and therapy, focusing on PA imaging-guided photothermal therapy (PTT) and discussing their imaging and therapeutic mechanisms and developments. Finally, the current challenges and potential opportunities of carbon-based materials for PA imaging-guided PTT are presented, and issues that researchers should be aware of when studying CBNM are provided.

中文翻译:

光声成像引导的碳基纳米材料在光热治疗中的应用:知识现状和最新进展

:碳基纳米材料(CBNM)由于其优异的理化性能,在各个领域得到了广泛的应用。特别是在肿瘤诊断和治疗领域,研究人员经常报道它们潜在的荧光、光声(PA)和超声成像性能,以及光热、光动力、声动力和其他治疗特性。随着CBNM功能的日益发展,其优异的成像特性和优越的肿瘤治疗效果使其成为极有前途的治疗诊断药物。本综述旨在整合本研究课题特定领域内的思考和研究信息,系统地呈现、总结和评论权威学者所做的努力。在这篇综述中,我们总结了碳基材料在肿瘤成像和治疗领域的探索工作,重点关注PA成像引导的光热治疗(PTT),并讨论了其成像和治疗机制和发展。最后,提出了碳基材料用于PA成像引导PTT的当前挑战和潜在机遇,并提出了研究人员在研究CBNM时应注意的问题。
更新日期:2024-03-26
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