Several risk factors have been identified that compromise the treatment outcome in patients with early-to-mid-stage cervical cancer (CC) who are primarily treated with radical surgery. However, there is no report on the impact of intraoperative frozen pathology examination of vaginal margins on the prognosis of patients with CC. This study aimed to conduct a randomized controlled trial (RCT) to determine whether selective vaginal resection can reduce the incidence of operative complications and the risk of postoperative radiotherapy. The impact of the length of the vagina removed in radical hysterectomy (RH) on prognosis and quality of life (QoL) for IB2-IIA2 CC patients will be investigated.

中文翻译：

---

根治性子宫切除术中阴道边缘的术中冰冻切片病理学对 IB2-IIA2 宫颈癌患者预后和生活质量的影响：多中心随机对照试验的研究方案。

已经确定了一些风险因素，这些因素会影响主要接受根治性手术治疗的早中期宫颈癌（CC）患者的治疗结果。但术中阴道切缘冰冻病理检查对CC患者预后的影响尚未见报道。本研究旨在进行随机对照试验（RCT），以确定选择性阴道切除术是否可以降低手术并发症的发生率和术后放疗的风险。将研究根治性子宫切除术 (RH) 中切除的阴道长度对 IB2-IIA2 CC 患者预后和生活质量 (QoL) 的影响。