The central feature of covalent organic frameworks (COFs) is crystallinity which is conducive to forming a uniform pore structure. However, synthesis of highly crystalline COFs based on stable covalent bonds remains formidable task. In this paper, a highly crystalline acylhydrazone COF-BD was synthesized in aqueous phase. The synthesis mechanism was proposed that the protonated hydrazide monomers dissolved in aqueous phase reacted with aldehyde monomers by deprotonation into the micellar. By investigating the effects of experimental parameters on the crystallinity of COF-BD, it was founded that under C9–COONa as surfactant, 80 °C, and 1.0 eq acetic acid as catalyst, acylhydrazone COF-BD with good crystallinity could be prepared. To prove the extensibility of this method, another acylhydrazone COF was prepared successfully.

中文翻译：

---

高结晶酰腙COF的水相合成

共价有机骨架（COF）的核心特征是结晶度，有利于形成均匀的孔结构。然而，基于稳定共价键的高度结晶COF的合成仍然是一项艰巨的任务。本文在水相中合成了高度结晶的酰腙COF-BD。提出了合成机理：质子化的酰肼单体溶解在水相中，通过去质子化进入胶束与醛单体反应。通过考察实验参数对COF-BD结晶度的影响，发现在C9-COONa为表面活性剂、80℃、1.0当量乙酸为催化剂下，可以制备出结晶度良好的酰腙COF-BD。为了证明该方法的可扩展性，成功制备了另一种酰腙COF。