This review paper explores the emerging field of environmentally sustainable approaches to the synthesis of Metal-Organic Frameworks (MOFs) incorporating copper nanoparticles for the treatment of Gram-negative bacterial infections. Focusing on green synthesis methods, the paper critically examines various strategies that emphasize eco-friendly principles, reducing environmental impact and resource utilization. The synthesis procedures and characterization techniques employed in these green MOF formulations are comprehensively analyzed. The review aims to consolidate recent research findings, providing an overview of the effectiveness, challenges, and potential applications of MOF-based Cu nanoparticles synthesized through environmentally conscious methods in addressing Gram-negative bacterial infections. This synthesis-focused review contributes to the evolving paradigm of sustainable antibacterial strategies, offering valuable insights for researchers and practitioners committed to both therapeutic efficacy and environmental responsibility.

中文翻译：

---

用于治疗革兰氏阴性细菌感染的包含铜纳米粒子的金属有机框架的环境可持续合成的新趋势

这篇综述论文探讨了环境可持续方法的新兴领域，用于合成包含铜纳米颗粒的金属有机框架（MOF），用于治疗革兰氏阴性细菌感染。本文以绿色合成方法为重点，批判性地研究了强调生态友好原则、减少环境影响和资源利用的各种策略。对这些绿色 MOF 配方中采用的合成程序和表征技术进行了全面分析。该综述旨在巩固最近的研究成果，概述通过环保方法合成的 MOF 基铜纳米粒子在解决革兰氏阴性细菌感染方面的有效性、挑战和潜在应用。这项以合成为重点的综述有助于可持续抗菌策略的不断发展，为致力于治疗功效和环境责任的研究人员和从业者提供了宝贵的见解。