This article aimed to review the current literature on the impact of continuous shedding of the COVID-19 virus in infected patients in relation to disease outcome variables and viral dynamics. Electronic databases PubMed, Google Scholar, and MedlinePlus were searched using relevant keywords, restricting the selection to thirty-two peer-reviewed articles and four gray literatures from the WHO websites. Findings from this study showed that several variables such as sex, age, immune status, treatments, and vaccines were found to affect the outcomes associated with the COVID-19 virus shedding. These findings highlight the need for further research using longitudinal whole-genome sequencing of the virus and its variants to increase the understanding.

本文旨在回顾有关感染患者中 COVID-19 病毒持续脱落对疾病结果变量和病毒动力学影响的最新文献。使用相关关键词对电子数据库 PubMed、Google Scholar 和 MedlinePlus 进行搜索，将选择范围限制为来自 WHO 网站的 32 篇同行评审文章和 4 篇灰色文献。这项研究的结果表明，性别、年龄、免疫状态、治疗和疫苗等几个变量会影响与 COVID-19 病毒脱落相关的结果。这些发现强调需要利用病毒及其变体的纵向全基因组测序进行进一步研究，以增进了解。