Purpose:This study aimed to evaluate the impact of the diverse stent size selection on the clinical and angiographic outcomes of Willis covered stent (WCS) for the treatment of skull base cerebrovascular diseases.Materials and methods:A total of 147 patients with 151 skull base cerebrovascular diseases treated with WCS in 3 centers between January 2015 and July 2022 were included in this study. Several parameters depicting stent size and parent artery condition were incorporated into the analysis of the outcomes.Results:Complete occlusion was found in 106 cases (68.2%) immediately after deployment and 126 cases (83.4%) after technical adjustment. In the multivariate logistics analysis, the difference between stent diameter and parent artery diameter (DD) was significantly associated with immediate endoleak without adjustment (odds ratio [OR]=0.410; p=0.005) and late endoleak (OR=0.275; p=0.028). In addition, differences between stent diameter and parent artery diameter at wide landing point (DSW) and differences between stent diameter and parent artery diameter at narrow landing point (DSN) was also was significant associated with immediate endoleak without adjustment and balloon re-dilation respectively.Conclusions:This study demonstrated that the diameter selection of the WCS was associated with the occurrence of endoleak during the treatment of skull base cerebrovascular diseases. Precise selection and evaluation of stent size and vessel condition were significant factors for skull base cerebrovascular diseases treated by WCS.Clinical ImpactThis study demonstrates a significant association between the diameter selection of the Willis covered stent (WCS) and the occurrence of endoleak in the management of skull base cerebrovascular diseases. The results offer valuable medical evidence that can inform stent selection for WCS. The study emphasizes the significance of precise evaluation of stent size and vessel condition as crucial factors in WCS procedures. These findings underscore the importance of meticulous consideration and individualized approaches to stent selection, ultimately improving treatment outcomes in clinical practice.

中文翻译：

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支架尺寸选择和血管评估对 Willis 覆膜支架治疗颅底脑血管疾病的影响：多中心回顾性分析

目的：本研究旨在评价不同支架尺寸选择对Willis覆膜支架（WCS）治疗颅底脑血管疾病的临床和血管造影结果的影响。材料与方法：共147例患者151个颅底本研究纳入2015年1月至2022年7月期间在3个中心接受WCS治疗的脑血管疾病。结果分析中纳入了描述支架尺寸和载瘤动脉状况的几个参数。结果：部署后立即完全闭塞106例（68.2%），技术调整后126例（83.4%）完全闭塞。在多变量逻辑分析中，支架直径和载瘤动脉直径 (DD) 之间的差异与未经调整的立即内漏（比值比 [OR]=0.410；p=0.005）和晚期内漏（OR=0.275；p=0.028）显着相关）。此外，宽着陆点处支架直径与载瘤动脉直径之间的差异（DSW）以及狭窄着陆点处支架直径与载瘤动脉直径之间的差异（D序列号）也分别与不调整即刻内漏和球囊再扩张显着相关。结论：本研究证明，颅底脑血管疾病治疗过程中，WCS直径选择与内漏的发生相关。支架尺寸和血管状况的精确选择和评估是 WCS 治疗颅底脑血管疾病的重要因素。临床影响本研究表明 Willis 覆膜支架 (WCS) 的直径选择与治疗中内漏的发生之间存在显着相关性。颅底脑血管疾病。结果提供了宝贵的医学证据，可以为 WCS 支架的选择提供参考。该研究强调了精确评估支架尺寸和血管状况作为 WCS 手术中关键因素的重要性。这些发现强调了仔细考虑和个体化支架选择方法的重要性，最终改善临床实践中的治疗结果。