IntroductionPossible resistance to recommended treatments for scabies has emerged recently. In response to anecdotal reports of a recent increase in treatment failure with permethrin, the British Association for Sexual Health and HIV (BASHH) released a statement alerting members to this.AimsTo examine attendances and the treatment pathways for scabies cases seen at local sexual health clinics.MethodologyA case note review of scabies attendances between January 2017 and December 2023 was conducted. Data collected included patient demographics, clinical information, and scabies treatment histories. Statistical analysis was performed.Results143 patients attended with scabies. The number of scabies cases did not appear to increase significantly from 2017 to 2023 ( p = .09). There was significant increase in median number of treatments per case per year over time ( p = .013). The number of individuals needing second-line treatments increased significantly over time ( p-trend < 0.001).DiscussionIndividuals with scabies are requiring more treatments to clear infection. Use of ivermectin has risen in the last year suggesting that second-line treatment is increasingly needed for eradication. Whilst treatment failure may be due to non-compliance with treatment and decontamination efforts for both index and contacts, the more recent change in findings could be attributed to a fall in permethrin efficacy.

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深入浅出：2017-2023 年疥疮管理评估

简介 最近出现了对推荐的疥疮治疗方法可能产生耐药性的情况。针对最近氯菊酯治疗失败的传闻增加，英国性健康和艾滋病毒协会 (BASHH) 发布了一份声明，提醒会员注意这一点。目的调查当地性健康诊所就诊的疥疮病例的就诊率和治疗途径方法对 2017 年 1 月至 2023 年 12 月期间疥疮就诊情况进行了病例记录审查。收集的数据包括患者人口统计、临床信息和疥疮治疗史。进行统计分析。结果143例疥疮患者。从 2017 年到 2023 年，疥疮病例数似乎没有显着增加 (p = .09)。随着时间的推移，每年每个病例的治疗次数中位数显着增加 (p = .013)。随着时间的推移，需要二线治疗的个体数量显着增加（p 趋势 < 0.001）。讨论 患有疥疮的个体需要更多的治疗来清除感染。去年伊维菌素的使用有所增加，这表明越来越需要二线治疗来根除病毒。虽然治疗失败可能是由于不遵守指示者和接触者的治疗和净化工作，但最近发现的变化可能归因于氯菊酯功效下降。