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We need more data to help guide the care of patients with cancer who develop kidney related problems
The BMJ ( IF 105.7 ) Pub Date : 2024-03-27 , DOI: 10.1136/bmj.q751
Shruti Gupta , David E Leaf

Healthcare staff caring for patients with cancer must have access to high quality and generalizable data regarding the toxicities and repercussions of cancer treatments Onconephrology, the intersection between oncology and nephrology, is a rapidly evolving field that has gained considerable interest over the past 15 years. Cancer treatments are often highly effective at targeting cancer cells but can lead to unexpected side effects, including acute kidney injury, hypertension, and electrolyte abnormalities. These kidney related toxicities can lead to temporary or permanent discontinuation of potentially lifesaving cancer treatments. Additionally, patients with cancer are living longer and could develop chronic kidney disease after bouts of acute kidney injury, thereby jeopardizing their eligibility for future treatments, in addition to placing them at increased risk of cardiovascular disease and death.1 It is therefore essential that nephrologists, oncologists, and other providers caring for patients with cancer have access to high quality and generalizable data regarding these toxicities and their repercussions. Despite some progress toward characterizing and understanding the kidney related toxicities associated with cancer treatments, …

中文翻译:

我们需要更多数据来帮助指导出现肾脏相关问题的癌症患者的护理

护理癌症患者的医护人员必须能够获得有关癌症治疗的毒性和影响的高质量和通用数据。肿瘤肾病学是肿瘤学和肾脏病学的交叉领域,是一个快速发展的领域,在过去 15 年中引起了人们的极大兴趣。癌症治疗通常能够非常有效地靶向癌细胞,但可能会导致意想不到的副作用,包括急性肾损伤、高血压和电解质异常。这些与肾脏相关的毒性可能导致暂时或永久停止可能挽救生命的癌症治疗。此外,癌症患者的寿命更长,并且在急性肾损伤后可能会发展为慢性肾脏疾病,从而危及他们未来治疗的资格,此外还会增加他们患心血管疾病和死亡的风险。1因此,肾脏病学家必须、肿瘤学家和其他照顾癌症患者的提供者可以获得有关这些毒性及其影响的高质量和通用数据。尽管在表征和理解与癌症治疗相关的肾脏相关毒性方面取得了一些进展,……
更新日期:2024-03-28
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