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Photothermal hydrogels for infection control and tissue regeneration
Frontiers in Bioengineering and Biotechnology ( IF 5.7 ) Pub Date : 2024-03-28 , DOI: 10.3389/fbioe.2024.1389327
Siyu Sun , Guangyang Jiang , Jianru Dong , Xi Xie , Jinfeng Liao , Yongqiang Tian

In this review, we report investigating photothermal hydrogels, innovative biomedical materials designed for infection control and tissue regeneration. These hydrogels exhibit responsiveness to near-infrared (NIR) stimulation, altering their structure and properties, which is pivotal for medical applications. Photothermal hydrogels have emerged as a significant advancement in medical materials, harnessing photothermal agents (PTAs) to respond to NIR light. This responsiveness is crucial for controlling infections and promoting tissue healing. We discuss three construction methods for preparing photothermal hydrogels, emphasizing their design and synthesis, which incorporate PTAs to achieve the desired photothermal effects. The application of these hydrogels demonstrates enhanced infection control and tissue regeneration, supported by their unique photothermal properties. Although research progress in photothermal hydrogels is promising, challenges remain. We address these issues and explore future directions to enhance their therapeutic potential.

中文翻译:

用于感染控制和组织再生的光热水凝胶

在这篇综述中,我们报告了对光热水凝胶的研究,这是一种专为感染控制和组织再生而设计的创新生物医学材料。这些水凝胶表现出对近红外 (NIR) 刺激的响应能力,改变其结构和特性,这对于医疗应用至关重要。光热水凝胶已成为医疗材料领域的一项重大进步,它利用光热剂(PTA)对近红外光做出反应。这种反应对于控制感染和促进组织愈合至关重要。我们讨论了三种制备光热水凝胶的构建方法,强调了它们的设计和合成,其中结合了 PTA 以实现所需的光热效应。这些水凝胶的应用表明,在其独特的光热特性的支持下,感染控制和组织再生得到了增强。尽管光热水凝胶的研究进展充满希望,但挑战仍然存在。我们解决这些问题并探索未来的方向以增强其治疗潜力。
更新日期:2024-03-28
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