Succinic acid (SA), one of the 12 top platform chemicals produced from biomass, is a precursor of various high value-added derivatives. Specially, 1 mol CO2 is assimilated in 1 mol SA biosynthetic route under anaerobic conditions, which helps to achieve carbon reduction goals. In this review, methods for enhanced CO2 fixation in SA production and utilization of waste biomass for SA production are reviewed. Bioelectrochemical and bioreactor coupling systems constructed with off-gas reutilization to capture CO2 more efficiently were highlighted. In addition, the techno-economic analysis and carbon sequestration benefits for the synthesis of bio-based SA from CO2 and waste biomass are analyzed. Finally, a droplet microfluidics-based high-throughput screening technique applied to the future bioproduction of SA is proposed as a promising approach.

中文翻译：

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琥珀酸生产的进展：增强二氧化碳固定以获得碳封存效益

琥珀酸（SA）是由生物质生产的 12 种顶级平台化学品之一，是各种高附加值衍生物的前体。特别地，1摩尔CO2在厌氧条件下被同化为1 mol SA生物合成途径，有助于实现减碳目标。在这篇综述中，增强 CO 的方法2综述了 SA 生产中的固定以及用于 SA 生产的废弃生物质的利用。利用废气再利用构建生物电化学和生物反应器耦合系统以捕获 CO2强调了更有效。此外，从CO合成生物基SA的技术经济分析和碳封存效益2并对废弃生物质进行了分析。最后，提出了一种基于液滴微流体的高通量筛选技术，作为未来 SA 生物生产的一种有前途的方法。