Metal–organic frameworks (MOFs) have garnered significant attention across various fields, particularly in the field of the separation sciences, owing to their appealing structures and unique properties including high surface-to-volume ratios, substantial porosity, and selective adsorption capabilities for diverse materials. On the road to objectives of this study, numerous MOFs have been proposed as stationary phases in both gas and liquid chromatography. This study presents a straightforward and efficient in situ method for immobilizing a specific MOF onto the surfaces of fused silica capillaries, with the aim of utilizing them as stationary phases in gas chromatography. Diverse pre-treatments of the fused silica capillaries and various coating methods, including dynamic coating and different in situ solvothermal growth techniques for MOF deposition onto the capillary surface, were systematically undertaken and meticulously examined. Results obtained from different of analytical techniques, including FESEM, EDX, FTIR, and XRD, affirm the successful immobilization and bonding of MOF nanoparticles onto the fused silica capillary surface. The prepared MOF@capillary emerges as a promising candidate for serving as a stationary phase in gas chromatography, particularly for the separation of various volatile organic compounds. This comprehensive study not only expands our understanding of MOF applications but also confirms the feasibility of employing MOF-coated capillaries in gas chromatographic separation processes.

Graphical abstract

中文翻译：

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MOF纳米晶在熔融石英毛细管上的原位溶剂热生长旨在制备新型气相色谱柱

金属有机框架（MOF）因其吸引人的结构和独特的性能（包括高比表面积、大量孔隙率和对多种物质的选择性吸附能力）而引起了各个领域的广泛关注，特别是在分离科学领域。材料。在实现本研究目标的过程中，许多 MOF 已被提议作为气相色谱和液相色谱的固定相。本研究提出了一种直接有效的原位方法，将特定的 MOF 固定到熔融石英毛细管的表面，目的是利用它们作为气相色谱中的固定相。系统地对熔融石英毛细管进行了多种预处理，并采用了多种涂层方法，包括动态涂层和用于将 MOF 沉积到毛细管表面的不同原位溶剂热生长技术。从不同分析技术（包括 FESEM、EDX、FTIR 和 XRD）获得的结果证实了 MOF 纳米颗粒成功固定和键合到熔融石英毛细管表面。所制备的 MOF@毛细管成为气相色谱固定相的有前途的候选者，特别是用于分离各种挥发性有机化合物。这项综合研究不仅扩大了我们对 MOF 应用的理解，而且证实了在气相色谱分离过程中使用 MOF 涂层毛细管的可行性。

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