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Vaccines to control tuberculosis in cattle
Science ( IF 56.9 ) Pub Date : 2024-03-29 , DOI: https://www.science.org/doi/10.1126/science.ado4333
Anita L. Michel

Tuberculosis (TB) has plagued humans around the globe for thousands of years and still causes 10 million new cases every year (1). The second leading cause of death from infectious disease in humans, TB also afflicts animals, both domestic and wild. Bovine TB in cattle causes socioeconomic implications as a result of decreased production, the compulsory slaughter of infected animals, and associated social knock-on effects (2). The BCG (Bacillus Calmette-Guérin) vaccine, which has been in use for 100 years, is currently the only vaccine available to protect children against human TB (caused by Mycobacterium tuberculosis); there is no TB vaccine for livestock (caused by the related bacterium Mycobacterium bovis). On page 1433 of this issue, Fromsa et al. (3) report field data from studies in Ethiopia that support the use of the human BCG vaccine in cattle, which could help eliminate bovine TB.

中文翻译:

控制牛结核病的疫苗

结核病 (TB) 已经困扰全球人类数千年,并且每年仍造成 1000 万新病例 ( 1 )。结核病是人类传染病死亡的第二大原因,它也影响家养和野生动物。由于产量下降、强制宰杀受感染动物以及相关的社会连锁反应,牛结核病会造成社会经济影响 ( 2 )。卡介苗(卡介苗)疫苗已使用 100 年,是目前唯一可用于保护儿童免受人类结核病(由结核分枝杆菌引起)的疫苗;没有针对牲畜的结核病疫苗(由相关细菌牛分枝杆菌引起)。在本期第 1433 页,Fromsa等人。 ( 3 ) 报告埃塞俄比亚研究的现场数据,这些数据支持在牛身上使用人类卡介苗疫苗,这有助于消除牛结核病。
更新日期:2024-03-29
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