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A successful desensitization in an adult patient with ARA-C infusion reaction
Journal of Oncology Pharmacy Practice ( IF 1.3 ) Pub Date : 2024-03-28 , DOI: 10.1177/10781552241242691
Yasemin Akgul Balaban 1 , Mustafa Ilker Inan 1 , Ali Selcuk 1 , Ozgur Kartal 1 , Haydar Zengin 2 , Tuba Bulduk 2
Affiliation  

IntroductionCytarabine (ARA-C) is an antimetabolite agent used especially in the treatment of hematologic malignancies. Infusion reactions have an important place among the side effects that may occur due to treatment. Clinical findings of infusion reactions resemble allergic reactions.Case Report47-year-old male patient with a diagnosis of B-cell Acute Lymphoblastic Leukaemia developed infusion reaction during ARA-C treatment.Management & OutcomeThere was no alternative treatment option for his existing malignant disease, we decided ARA-C desensitization.DiscussionWe would like to describe a successful desensitization protocol in an adult patient who experienced a reaction during ARA-C infusion.

中文翻译:

一名患有 ARA-C 输注反应的成年患者成功脱敏

简介阿糖胞苷 (ARA-C) 是一种抗代谢药物,特别用于治疗血液恶性肿瘤。输注反应在治疗可能发生的副作用中占有重要地位。输液反应的临床表现类似于过敏反应。病例报告47岁男性患者,被诊断为B细胞急性淋巴细胞白血病,在ARA-C治疗期间出现输液反应。管理与结果他现有的恶性疾病没有其他治疗选择,我们决定 ARA-C 脱敏。讨论我们想描述一个在 ARA-C 输注期间出现反应的成年患者的成功脱敏方案。
更新日期:2024-03-28
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