This study aims to compare the diagnostic value of balloon expulsion test and anorectal manometry in patients with constipation through meta-analysis. Databases, encompassing PubMed, EMBASE, Cochrane Library, Web of Science, etc. were searched for all English publications on the diagnosis of constipation using balloon expulsion test and anorectal manometry. The publication date was restricted from the inception of the databases until December 2022. Data analysis was carried out utilizing Stata 15.0 and Meta-Disc 1.4 software. Thirteen studies involving 2171 patients with constipation were included. According to the meta-analysis, the balloon expulsion test showed a pooled sensitivity of 0.75 (95% CI: 0.72-0.77), a pooled specificity (Spe) of 0.67 (95% CI: 0.62-0.72), a pooled positive likelihood ratio (+LR) of 3.24 (95% CI: 1.53-6.88), a pooled negative likelihood ratio (-LR) 0.35 (95% CI: 0.23-0.52) and a pooled diagnostic odds ratio (DOR) of 9.47 (95% CI: 3.27-27.44). For anorectal manometry, the pooled Sen, Spe, +LR, -LR and DOR were 0.74 (95% CI: 0.72-0.76), 0.73 (95% CI: 0.70-0.76), 2.69 (95% CI: 2.18-3.32), 0.35 (95% CI: 0.28-0.43), and 8.3 (95% CI: 5.4-12.75), respectively. The area under the summary receiver operating characteristic curve areas for balloon expulsion test and anorectal manometry were 0.8123 and 0.8088, respectively, with no statistically significant disparity (Z = -0.113, P > 0.05). Both the balloon expulsion test and anorectal manometry demonstrate comparable diagnostic performance, each offering unique advantages. These diagnostic procedures hold significance in the diagnosis of constipation.

中文翻译：

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球囊排出试验和肛门直肠测压对便秘患者的诊断价值：系统评价和荟萃分析。

本研究旨在通过荟萃分析比较球囊排出试验和肛门直肠测压对便秘患者的诊断价值。检索了 PubMed、EMBASE、Cochrane Library、Web of Science 等数据库中关于使用球囊排出试验和肛门直肠测压诊断便秘的所有英文出版物。发布日期从数据库建立之日起至2022年12月。数据分析是利用Stata 15.0和Meta-Disc 1.4软件进行的。纳入了 13 项研究，涉及 2171 名便秘患者。根据荟萃分析，球囊排出试验显示汇总敏感性为 0.75 (95% CI: 0.72-0.77)，汇总特异性 (Spe) 为 0.67 (95% CI: 0.62-0.72)，汇总阳性似然比(+LR) 为 3.24 (95% CI: 1.53-6.88)，汇总阴性似然比 (-LR) 0.35 (95% CI: 0.23-0.52)，汇总诊断优势比 (DOR) 为 9.47 (95% CI) ：3.27-27.44）。对于肛门直肠测压，汇总的 Sen、Spe、+LR、-LR 和 DOR 分别为 0.74 (95% CI: 0.72-0.76)、0.73 (95% CI: 0.70-0.76)、2.69 (95% CI: 2.18-3.32) 、0.35（95% CI：0.28-0.43）和 8.3（95% CI：5.4-12.75）。球囊排出试验和肛门直肠测压的受试者工作特征曲线下面积分别为 0.8123 和 0.8088，没有统计学上的显着差异（Z = -0.113，P > 0.05）。球囊排出测试和肛门直肠测压法均表现出可比的诊断性能，且各自具有独特的优势。这些诊断程序对于便秘的诊断具有重要意义。